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There was n’t anything particularly unusual about the squash vine — just a slightly bitter gustation . But that all changed when two women in France startedlosing their pilus .
The cleaning lady did n’t know each other , nor did they get their squash racquets from the same seller . Still , they both formulate what ’s known as cucurbit poisoning , or " toxic squash syndrome , " allot to a young report of the two display case , release today ( March 28 ) in the journalJAMA Dermatology .
In one of the case , a woman and her family developed symptom of food poisoning — nausea , vomit and looseness of the bowels — hour after eat a bitter - tasting pumpkin soup . About a hebdomad later , the woman experienced square hair loss that affected a large part of her scalp , but none of her family members fall back their fuzz . [ 27 Oddest Medical Cases ]
In the second case , another woman had severe vomiting about an hour after eat a virulent - smack squash , but no one else who ate the veggie got sick . Roughly three week later , she turn a loss a massive amount of haircloth from her head , as well as from her underarms and pubic area .
Bitter squash
As it plough out , some members of the Cucurbitaceae family line — which includes pumpkin vine , squeeze , melon vine andcucumbers — can produce a group of chemicals know as cucurbitacins . Not only do these chemical substance savor virulent , but they can also have toxic effect on human electric cell .
Normally , farmers school these plant to produce little to no cucurbitacins , because people do n’t care thebitter taste . But in some post , such as when there ’s inadvertent cross - pollination of crop or when plants grow in the wild , some varieties may comprise high levels of the chemicals . This creates a potentially toxic , bitter - tasting , uneatable food .
The problem , however , is that the acid - tasting vegetable looks no dissimilar from a normal one , and a somebody ca n’t tell the difference until they take a bite .
Toxic squash syndrome
Although it ’s rare , other cases of cucurbit poisoning have been described in the medical literature ; in those cases , people evolve food for thought poisoning after eat acid - tasting squash , courgette and other gourds , grant to the newfangled reputation . But these are the first two report cases link up the phthisis of bitter - taste gourds with hair red , according to the case report author , Dr. Philippe Assouly , a skin doctor at Saint - Louis Hospital in Paris . [ 7 Foods you may Overdose On ]
Assouly write that he suspects that toxic compounds in the plant have a exchangeable upshot on hair follicles as do somechemotherapy drugs , which can lead to temporary haircloth loss .
But because hair loss is a completely new observance that is potentially associated with picture to cucurbitacins , it ’s not clear why it pass off in these caseful , say Dr. Zane Horowitz , a toxicologist and aesculapian director of the Oregon Poison Center in Portland , who was not involve in the case . Cucurbit poisoning is a very rarefied syndrome , and the toxin involved has not been well - analyze , Horowitz noted .
In 2012 , parking brake way physicians at Oregon Health & Science University saw two patients with toxic squash syndrome , both of whom had eaten squash from a home garden . The physicians thenreviewed the recordsfrom the Oregon and Washington state poison centers and identified about 17 other cases of cucurbit intoxication that had occurred over a 12 - year period .
In a more recentreview , published in January 2018 in the Journal of Clinical Toxicology , a French poison center reported more than 350 cases offood poisoninglinked with virulent - taste squash racquets that take shoes between 2012 and 2016 . About 56 percent of those cases involved squash buy at a entrepot , and in 26 percentage of the cases , the veggie came from a nursing home garden , harmonize to the finding .
Squash fan require to be aware that if they eat one of these popular vegetable and it tastes acerb , they should stop eating it immediately , Horowitz told Live Science . What ’s clear in all these case reports is that in high spirits spirit level of the toxin make vegetables smack bitter , and those gamy grade of toxin can put a person at high risk for symptom , he say .
As for the two French women who lost their hair , the hair on the head of the woman who ate the pumpkin soup had regrown less than 1 inch ( 2 centimeter ) two months after the incident . The 2nd charwoman had regrown short hair , of more than 2 inches ( 6 cm ) , on most areas of her scalp six month by and by .
Originally published onLive Science .
