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Men who take ethical drug pain medication for long periods may be at increased risk of erectile dysfunction , a new study paint a picture .
In the study , Isle of Man who took high doses ofopioid medicationfor at least four months were 50 percent more potential to be treat for cavernous disfunction ( ED ) than those who did not take opioid medicament , the researchers said .
The results held even after the researchers took into chronicle factors that could increase the hazard of ED , such as years , smoke and imprint .
The cogitation found an association , and can not prove a cause - and - effect tie-in between take opioid medicine and erectile disfunction . The study did not follow human over clock time , so it can not tantalize out which came first : handling for pain , or for ED .
However , the finding bestow to a farm dead body of research relate pain drug to erection problems . A 2011 subject field published in The Journal of Urology found that men who on a regular basis demand nonsteroidal anti - inflammatory drug ( NSAIDs ) were at mellow risk oferectile dysfunctionthan men who took the medications less ofttimes . And other narcotic , such as heroine , are also known to increase ED endangerment , experts say .
While there is no question that opioid handling is appropriate for some mass , there ’s increased evidence that prolonged use can cause a host of problems , including addiction , overdose and sleep apnea , said study research worker Dr. Richard Deyo , an investigator with the Kaiser Permanente Center for Health Research in Portland .
man " need to be cognizant that [ ED ] is a potential side event of farseeing - term and high - Elvis opioid medicament , " Deyo said .
Deyo and colleagues analyzed selective information from 11,327 men in Oregon and Washington who visit a doctor for back painfulness in 2004 . They looked at ethical drug six months before and six months after the visit , to see if the human race had received opioid , ED drugs or testosterone replacement therapy .
They found that 19 percentage of man who take opioid medications for extend periods ( four month or more ) also have ethical drug ED drug , whereas just 7 percentage of men who did not take opioids also received ED drugs , the researchers order .
Older gentleman , those with depression and those who assume sedatives for sleep or anxiety were also more potential to take ED drug .
The study looked at prescriptions forED drugsas a mark for hard-on problem , but it ’s possible some man had erection problems and were not treated with drug . The study also did not inquire participants whether they had diabetes , a shape also bonk to increase the risk of ED .
Dr. Andrew Kramer , a urologist and surgeon at the University of Maryland Medical Center , said that he commonly sees patient who take pain medications and also have erection problems .
Kramer enjoin he was not surprise by the outcome of the Modern study , because opiod medications can benumb corporal functions such as appetite and answer to sexual stimulus . " Everything is dull , " Kramer said .
Some previous research has suggested that opioid medications low-toned testosterone levels in men , but experts emphasize that " downcast T " can sometimes be a completely separate condition from cavernous disfunction , said Dr. Jessica Kreshover a urologist at North Shore - Long Island Jewish Arthur Smith Institute for Urology in Lake Success , New York , enounce .
More enquiry is needed to explore the connection suggest by the new survey , Kreshover tell . The study grouped affected role take in ED drugs together with patient role taking testosterone replacement therapy , but opioids may have unlike effects on testosterone spirit level and cavernous occasion , she enounce .
The new study is issue today ( May 15 ) in the journal Spine .
